The Future of Cardiovascular Therapeutics.

Review on the Symptoms, Transmission, Therapeutics Options and Control the Spread of the Disease of COVID-19

An unprecedented outbreak of pneumonia in Wuhan City, Hubei province in China emerged in December of 2019. COVID-19 is a betacoronavirus which consisted of a single-stranded ribonucleic acid (RNA) structure that belongs to the Coronavirinae subfamily. With respect to the large number of infected people that were exposed to the alive animals (bats, snakes, pangolins) in Wuhan City, China, it is ...

The Future of Cell Therapy and Tissue Engineering in Cardiovascular Disease: The New Era of Biological Therapeutics

Functionalized CNTs for delivery of therapeutics

Carbon nanotubes (CNTs) are high aspect ratio allotropes of carbon. Because of their unique physical and chemical characteristics, they are nominated for a vast variety of applications in the biomedical field. Their very low solubility is the only problem of them which is solved by different methods of Functionalization. After discoveries in the last few years of the capacity of CNTs to penetra...

miRNA therapeutics in cardiovascular diseases: promises and problems

microRNAs (miRNAs) are a novel class of non-coding RNAs which found their way into the clinic due to their fundamental roles in cellular processes such as differentiation, proliferation, and apoptosis. Recently, miRNAs have been known as micromodulators in cellular communications being involved in cell signaling and microenvironment remodeling. In this review, we will focus on the role of miRNA...

C-reactive protein and other markers of inflammation in hemodialysis patients

Background: Hemodialysis patients are at greater risk of cardiovascular disease. Higher than expected cardiovascular morbidity and mortality in this population has been attributed to dislipidemia as well as inflammation. The causes of inflammation in hemodialysis patients are multifactorial. Several markers were used for the detection of inflammatory reaction in patients with chronic renal dise...

The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities

In the past decade, the incidence of type 2 diabetes (T2D) has rapidly increased, along with the associated cardiovascular complications. Therefore, understanding the pathophysiology underlying T2D, the associated complications and the impact of therapeutics on the T2D development has critical importance for current and future therapeutics. The prevailing feature of T2D is hyperglycemia due to ...